Eye Imaging Genetics Knowledge Portal (Eye-KP)

Welcome to Eye-KP

Integrating knowledge and data of eye for multi-organ connections.

A GWAS browser built with the PheWeb tool to explore GWAS results, which covers a wide range of brain, heart, and eye imaging traits. In particular, two categories of eye imaging traits, retinal optical coherence tomography (OCT) and fundus tomography were added recently.

2. Eye-brain connections

Systematic cross-organ analysis of eye-brain connections using retina and brain imaging endophenotypes.

Reference:

Zhao, B., Li, Y., Fan, Z. et al. Eye-brain connections revealed by multimodal retinal and brain imaging genetics. Nat Commun 15, 6064 (2024). LINK

3. GWAS Summary Statistics Download

Eye imaging GWAS summary statistics can be downloaded at https://doi.org/10.5281/zenodo.11217687.

Welcome to check out our

Brain Imaging Genetics Knowledge Portal (BIG-KP) and

Heart Imaging Genetics Knowledge Portal (Heart-KP)

Change log:

Feb 17, 2023: Initial set up

May 20, 2024: Download link of eye imaging GWAS summary statistics added

July 29, 2024: Reference paper updated